Tibiofemoral joint structural change from 2.5 to 4.5 years following ACL reconstruction with and without combined meniscal pathology

X Wang; KL Bennell; Y Wang; TV Wrigley; A Van Ginckel; K Fortin; DJ Saxby; FM Cicuttini; DG Lloyd; CJ Vertullo; JA Feller; T Whitehead; P Gallie; AL Bryant

Journal article

Tibiofemoral joint structural change from 2.5 to 4.5 years following ACL reconstruction with and without combined meniscal pathology

X Wang, KL Bennell, Y Wang, TV Wrigley, A Van Ginckel, K Fortin, DJ Saxby, FM Cicuttini, DG Lloyd, CJ Vertullo, JA Feller, T Whitehead, P Gallie, AL Bryant

BMC Musculoskeletal Disorders | BMC | Published : 2019

DOI: 10.1186/s12891-019-2687-9

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Abstract

Background: People who have had anterior cruciate ligament reconstruction (ACLR) are at a high risk of developing tibiofemoral joint (TFJ) osteoarthritis (OA), with concomitant meniscal injury elevating this risk. This study aimed to investigate OA-related morphological change over 2 years in the TFJ among individuals who have undergone ACLR with or without concomitant meniscal pathology and in healthy controls. A secondary aim was to examine associations of baseline TFJ cartilage defects and bone marrow lesions (BML) scores with tibial cartilage volume change in ACLR groups. Methods: Fifty seven ACLR participants aged 18-40 years (32 isolated ACLR, 25 combined meniscal pathology) underwent ..

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University of Melbourne Researchers

Kim Bennell Author

Adam Bryant Author

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Grants

Awarded by Horizon 2020 Framework Programme

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council (NHMRC, project grant 628850). YW is the recipient of an NHMRC Career Development Fellowship (Clinical level 1, #1065464). KB is the recipient of a NHMRC Principal Research Fellowship (#1058440). ALB is the recipient of a NHMRC Career Development Fellowship (#1053521). AVG is supported by a FWO (Pegasus)<SUP>2</SUP> EU Marie-Sklodowska Curie Fellowship (Horizon 2020 grant #665501). The funding source had no role in the: study design; collection, analysis and interpretation of data; in the writing of the manuscript; and in the decision to submit the manuscript for publication.